News and Events

Evolution of molecular targets in melanoma treatment

10 February 2020

This paper discusses that there is still an unmet need in melanoma treatment: A significant population of patients did not respond to either BRAF inhibitors or immune checkpoint inhibitors, or would develop drug resistance even when MEK inhibitors were added to the treatment. It also discusses some possible targets for melanoma treatment.

Melanoma in Children and Teenagers

10 February 2020

While surgical and medical management still follows adult guidelines, recently there has been a better understanding of specific characteristics of pediatric melanoma. First pediatric clinical studies have been conducted.

Clinical Epidemiology of Melanoma

10 February 2020

Recently, algorithms have been developed that combine information about various phenotypic characteristics to derive an overall summary risk score. Such tools are being tested as decision aids to stratify individuals into potential screening programs according to their future risk of melanoma.

Cytokines (IL-2, IFN, GM-CSF, etc.) Melanoma

10 February 2020

This chapter summarizes the development and use of cytokines as single agents or in combination in the treatment of patients with advanced metastatic melanoma.

Models for Predicting Melanoma Outcome

10 February 2020

This chapter presents clinical applications, criteria, challenges, and opportunities for interpreting and building tools for predicting melanoma outcomes.

Biomarkers for Melanoma

10 February 2020

This chapter reviews tumor tissue-based biomarkers, tumor environment-based biomarkers, soluble biomarkers of the peripheral blood, as well as treatment-associated biomarkers. These biomarkers might not only be useful for diagnostics, prognostication, and prediction of treatment outcomes but in particular for the continuous monitoring of a patient’s course of disease over time.

Biopsy of Suspected Melanoma

10 February 2020

This chapter describes important considerations when performing a biopsy of a lesion suspicious for melanoma, commonly used biopsy techniques, and their applications to maximize biopsy accuracy in the initial diagnosis of melanoma.

Melanoma Prognosis and Staging

10 February 2020

This chapter reviews the prognostic factors relevant to current melanoma practice with an emphasis on factors that have significance in contemporary statistical analyses, using the eighth edition AJCC melanoma staging system and an international database analysis as a framework.