News and Events

Single-cell analysis reveals new evolutionary complexity in uveal melanoma

3 February 2020

Uveal melanoma is a highly metastatic cancer that, in contrast to cutaneous melanoma, is largely unresponsive to checkpoint immunotherapy. This recent single-cell analysis study identified the checkpoint marker LAG3 as a potential candidate for immune checkpoint blockade in patients with high risk uveal melanoma.

DMAS shows potential in treating NRAS-mutated melanoma

29 January 2020

In this recent study, the therapeutic potential of β,β-dimethylacrylshikonin (DMAS) was investigated on melanoma. It showed that BRAF as well as NRAS-mutated metastatic human melanoma cell lines were treated successfully in vitro and in vivo.